Ceasefire talks between the United States and Iran, mediated by Pakistan in Islamabad, have failed to produce an agreement, according to U.S. Vice President JD Vance. This diplomatic setback poses a direct threat to Pakistan's national survival, as the country finds itself caught between the U.S. and Iran. With the U.S. relying on Pakistan for financial aid and security, and Iran being a neighboring country, the stakes are high. The situation is further complicated by Pakistan's military commitments under the '2025 Strategic Mutual Defense Agreement' with Saudi Arabia, which could force Pakistan to defend Saudi territory if conflict escalates. If negotiations collapse, the U.S. may seek access to Pakistani airbases for military operations against Iran, risking Iranian retaliation and potential missile strikes on Pakistan. This could lead to internal civil unrest, particularly given Pakistan's large Shia population. Additionally, militant groups along the 900-kilometer border with Iran may exploit the chaos, leading to increased violence. A failed summit could halt border trade, essential for the Balochistan region, and trigger a refugee crisis that Pakistan cannot afford. Overall, Pakistan faces a precarious situation that could destabilize the state.