Matteo Berrettini will take on Roberto Bautista Agut in the first round of the 2026 Monte-Carlo Masters on April 7 at the Monte Carlo Country Club in Roquebrune-Cap-Martin, France. This matchup is crucial for both players, as they have struggled with form this season. Berrettini has had a quarterfinal run at the Rio Open, while Bautista Agut's best results include Round of 16 finishes at the Open Occitanie and a Challenger event. Historically, Berrettini holds a significant advantage with a 4-1 head-to-head record against Bautista Agut, having won their last four encounters. Betting odds reflect Berrettini's status as the favorite, with a moneyline of -325. Analysts predict that if Berrettini can maintain his aggressive play and effective serving, he is likely to win in straight sets. Betting tips suggest the match will feature at least 20 games, and Berrettini is expected to win at least one set with a score of 6-4 or better.