The United States and Iran failed to reach an agreement after extensive negotiations in Islamabad, Pakistan, which lasted 21 hours. Vice President JD Vance announced that the US returned without a breakthrough, emphasizing that Iran did not accept Washington's terms regarding nuclear weapons and the strategic Strait of Hormuz. Iranian officials, including Parliament Speaker Mohammad Bagher Ghalibaf and Foreign Minister Abbas Araghchi, accused the US of making excessive demands that hindered progress. The talks aimed to address critical issues such as a potential extension of the ceasefire and phased sanctions relief but ultimately sidestepped the core concerns previously highlighted by the Trump administration. Vance described the atmosphere during the discussions as tense, with fluctuating moods from both sides. Despite achieving a fragile ceasefire a week prior, the failure to secure a deal represents a significant setback for both nations, with Iran signaling it is not eager for further negotiations.