The Ostrow School of Dentistry at the University of Southern California has launched the Smart Note system, a groundbreaking AI-enabled tool designed to enhance the diagnostic process for orofacial pain. Developed by faculty members Glenn Clark and Anette Vistoso, the system addresses the challenge of misdiagnosis, which affects up to 14% of new patient encounters, as noted in a study published in the American Journal of Medicine. The Smart Note system integrates three web applications to streamline patient interactions, improve data collection, and enhance diagnostic accuracy, achieving 93% accuracy in clinical trials. It specifically excels in diagnosing conditions with distinct symptom patterns, such as trigeminal neuralgia and burning mouth syndrome, boasting accuracies over 97% and 98%, respectively. The system not only aids clinicians in making informed decisions but also actively involves patients in their care through regular follow-ups and feedback mechanisms. As the Smart Note system evolves, plans are underway to incorporate voice capabilities and expand its application to other medical fields reliant on clinical reasoning, reinforcing the notion that while AI can assist, it cannot replace the essential human connection in healthcare.