Sentebale, a charity co-founded by Prince Harry (Duke of Sussex) in honor of his late mother, Princess Diana, has filed a defamation lawsuit against him in the High Court of Justice in London. The charity, which supports young people living with HIV in Botswana and Lesotho, claims that a media campaign initiated on March 25, 2025, has caused significant reputational damage and operational disruptions. Harry and his associate Mark Dyer are being sued for either libel or slander, although specific details of the lawsuit remain undisclosed. The lawsuit arises amid internal conflicts within Sentebale, which surfaced in 2023 over disagreements regarding fundraising strategies. Both Harry and Prince Seeiso stepped down as patrons in March 2025, citing a breakdown in relations with the charity's board. The Charity Commission for England and Wales later criticized both parties for allowing their disputes to become public, which harmed the charity's reputation. This lawsuit marks a significant turn for Harry, who has primarily been a claimant in legal actions against British tabloids regarding privacy issues.